Dr Stephen Hyer - Specialist in Endocrinology, Diabetes & General Medicine
RESEARCH
Invited lectures
Imperial College Masterclass, 2020
Obesity and Gestational Diabetes
St Bede’s Conference Centre, 2019
Diabetes Update, Long term conditions
Postgraduate lecture series, Education Centre, St Helier Hospital, 2019
Metabolic syndrome
Ian Smith Memorial lecture, Sutton & District Medical Society, 2019
Harold Shipman: Retelling the story
Epsom Medical Society, 2018
Harold Shipman: Serial killer and best loved doctor
The Society of Chiropodists & Podiatrists, 2018
Update on diabetes for podiatrists
Primary Care Conference, Birmingham 2018
The Global Diabetes Epidemic
BMJ Masterclass, Manchester 2015
GP General Update-Endocrinology
Royal College of Physicians, 2014
Medical complications of pregnancy- Type 1 diabetes in pregnancy
Diabetes Masterclass, 2014
Diabetes in pregnancy-new thinking
37th Annual Meeting of European Thyroid Association, Leiden, 2013
Personalised approach in the management of well differentiated thyroid cancer:
Ablation with low dose radioiodine
5th International Congress for Fertility & Genetics, Amman, 2013
Thyroid disorders in Pregnancy
Diabetes in Pregnancy
Diabetes Masterclass, 2011
Thyroid disorders in diabetes
The 2nd joint JSED-AACE Congress, 2010
Hyponatraemia
The Medical Society of London, 2009
Masterclass in thyroid cancer
11th European Congress of Endocrinology, Istanbul, 2009
Pregnancy after exposure to radioiodine
The Royal Society, London, 2007
Masterclass in advanced cancer medicine: Thyroid cancer
Royal College of Pathologists, London, 2006
UK Key Advances in Effective management of Thyroid Cancer
Early and late toxicity of radioiodine
Royal Society of Medicine, London, 2006
Medicine for Old Age Psychiatrist
Thyroid disease in the elderly
Royal College of Pathologists, London, 2004
UK Key Advances in Clinical Practice –thyroid disease
Medullary thyroid carcinoma
Royal Pharmaceutical Society, London, 2003
New advances in Diabetes
Institute of Cancer Research, London, 2003
Endocrine aspects of thyroid cancer
Faculty of Medicine, Addis Ababa University, 2003
Thyroid disease in developing countries
Publications
1. Hyer SL, Knell AJ.
Cirrhosis and haemolysis complicating methyldopa treatment.
Brit Med J 1977 1:879.
2. Nigram BK, Hyer SL, Taylor EJ, Guha T.
Intrathoracic chemodectoma with noradrenaline secretion.
Thorax 1981 36:66-68.
3. Hyer SL, Taylor D, Barham J, Wilson J, Shaw J, Vince FP.
The effects of propranolol and metoprolol on skin blood flow in diabetic patients.
Brit J Clin Pharmac 1987 23:769-771.
4. Hyer SL, Sharp PS, Brooks RA, Burrin JM, Kohner EM.
Serum IGF-1 concentration in diabetic retinopathy.
Diabetic Medicine 1988 5:356-360.
5. Hyer SL, Sharp PS, Brooks RA, Burrin JM, Kohner EM
Progression of diabetic retinopathy and changes in serum IGF-1 during CSII.
Hormone & Metabolic Res 1989 21:18-22.
6. Hyer SL, Sharp PS, Brooks RA, Burrin JM, Kohner EM
Failure to suppress GH secretion after 2 weeks trteatment with atropine or propanthelene in diabetics with proliferative retinopathy.
Acta Endocrinologica 1988 119:61-68.
7. Hyer SL, Sharp PS, Brooks RA, Burrin JM, Kohner EM
A 2 year follow-up study of serum IGF-1 in diabetics with retinopathy.
Metabolism 1989 38:586-9.
8. Hyer SL, Froyd HE, Kohner EM.
The effect of the NovoPen on glycaemic control and patient independence in diabetics with visual impairment.
Practical Diabetes 1988 5:197-99.
9. Hyer SL, Sharp PS, Brooks RA, Burrin JM, Kohner EM
Continuous subcutaneous octreotide infusion markedly suppresses IGF-1 levels whilst only partially suppressing GH secretion in diabetics with retinopathy.
Acta Endocrinologica 1989 120:187-194.
10. Hyer SL, Kohner EM, Davies G, Mackay EM, Vandenburg MJ.
Effect of two beta antagonists (dilevalol and propranolol) on retinal blood flow; a double blind placebo controlled study.
Journal of Hypertension 1989 7:S268-9.
11. Hyer SL, Kohner EM
Aspects of GH control in diabetes.
Australian & New Zealand J Ophthalmol 1990 18:33-39.
12. Davies G, Hyer SL, Kohner EM.
Macular blood flow response to acute reduction of plasma glucose in diabetic patients by the blue light entoptic technique.
Ophthalmology 1990 97:160-164.
13. Hyer SL, Gilbey S, Kohner EM, Bloom SR.
The growth hormone response to galanin in diabetics with retinopathy.
Exp Clin Endocrinol 1991 10:11-15.
14. Hyer SL, Richardson JH, Brown M, Lever AML, Nussey SS.
Progressive flaccid myelopathy associated with HTLV-1
Lancet 1991 338:994.
15. Hyer SL, Rodin DA, Tobias JH, Leiper A, Nussey SS.
Growth hormone deficiency during puberty reduces adult bone mineral density
Arch Dis Child 1992 67:1472-74.
16. Hyer SL, Soo SC, Nussey SS.
Spontaneous haemorrhage into a pituitary tumour after streptokinase therapy.
Postgrad Med J 1993 69:244.
17. Nussey SS, Hyer SL, Brada M, Leiper AD.
Bone mineralisation after treatment of growth hormone deficiency in survivors of childhood malignancy.
Acta Paediatr Suppl 1994 399:9-14.
18. Hyer SL, Thomas DM, Polak JM, Nussey SS.
Malignant insulinoma in pregnancy presenting as hypothermia.
J Obs Gynaecol 1995 15:34-36.
19. Zomas A, Marsh J, Harrison N, Hyer SL
Rapid progression of fibrosing alveolitis and thyrotoxicosis after antithymocyte globulin therapy for aplastic anaemia.
Annals of Haematol 1995 71:49-51.
20. Hyer SL
Improving the effectiveness of R&D in Trust Hospitals
British Journal of Health Care Management 1997 3:600-1.
21. Soper CPR, Barron JL, Hyer SL
Long term glycaemic control directly correlates with glomerular filtration rate in early IDDM before the onset of microalbuminuria.
Diabetes Medicine 1998 15:1010-1014
22. Hyer S, Wilcox H.
An ethical code for everybody in health care: A universal code should start with basic human rights.
British Medical Journal 1998 316:1459-60
23. Hyer SL, Duckworth K, Jones C.
Managing erectile disorders in diabetes: the one stop andrology clinic
Practical Diabetes International 1998 15: 225-226
24. Vini L, Hyer SL, Pratt B, Harmer C.
Good prognosis in thyroid cancer found incidentally at surgery for thyrotoxicosis
Postgraduate Med J 1999 75: 169-170
25. Nutting C, Hyer SL, Vini L, Harmer C
Failure of TSH rise prior to radioiodine therapy for thyroid cancer; implications for treatment
Clinical Oncology 1999 11:269-271
26. Vini L, Hyer SL, Pratt B, Harmer C.
Management of differentiated thyroid cancer diagnosed during pregnancy
European Journal of Endocrinology 1999 140:404-406[1]
27. Hyer SL, Vini L, Pratt B, Harmer C.
Medullary thyroid cancer: multivariate analysis of prognostic factors influencing survival[2]
European Journal of Surgical Oncology 2000 26:686-690
28. Plank M and Hyer SL
Clinical implications of foot pressures during normal gait
The Diabetic Foot 2000 3 (3) 100-104
29. Andrews, P.A., Hyer, S.L. and Wilcox, H.
Role of LRECs in review of MREC decisions.
British Medical Journal 2000. 320:7248
30. L Vini, S Hyer, A Al-Saadi, B Pratt, Harmer C
Prognosis for fertility and ovarian function after treatment with
radioiodine for thyroid cancer
Postgraduate Medical Journal 2002; 78 92-93
31. Hyer SL. Vini L, O’Connell M, Pratt B., Harmer C.
Testicular dose and fertility in men following I-131 therapy for thyroid cancer
Clinical Endocrinology 2002 56, 755-758[3]
32. Hyer SL
Type 2 diabetes is really a vascular disease
GP Update 2002 292-8
33. Vini L, Hyer SL, Marshall S, A’Hern R, Harmer C
Long-term results in elderly patients with differentiated thyroid cancer
Cancer 2003 97 (11) 2736 - 2742
34. Taylor H, Hyer S, Vini L, Pratt B, Cook G, Harmer C.
Diagnostic 131I whole body scanning after thyroidectomy and ablation for differentiated thyroid cancer.
European Journal of Endocrinology 2004 150 (5) 649-653
35. Hyer SL, Newbold K, Harmer C.
Familial medullary thyroid cancer: clinical aspects and prognosis.
European J. Surg. Oncol 2005 31 415-419.
36. Hyer SL, Shehata H.
Gestational Diabetes.
Current Obstetrics & Gynaecology 2005 15 (6) 368-374.
37. Haq M, Hyer S, Flux G, Cook G, Harmer C
Differentiated thyroid cancer presenting with thyrotoxicosis from functioning metastases
Brit J Radiology 2007 80 (950) e38-43
38. Hyer SL, Kong A, Pratt B, and Harmer CL
Salivary gland toxicity following 131I therapy for thyroid cancer
Clinical Oncology 2007 19 (1) 83-86
39. Patel S, Hyer SL, Barron J.
Glomerular Filtration Rate Is a Major Determinant of the Relationship between 25-Hydroxyvitamin D and Parathyroid Hormone
Calcified Tissue International 2007 80:221-226
40. Hyer SL, McAleese J, Newbold K, Harmer CL
Neuroendocrine carcinoma arising in soft tissue: Three case reports and literature review
World Journal Surgical Oncology 2007 5:77-79
41. Hyer SL, Plank M, Rodin DA, Patel S.
Falls, Postural stability and diabetic neuropathy: a study of post-menopausal women with type 2 diabetes mellitus using a footmat system
Diabetic Foot 2007 10:210-214
42. Kapoor N, Sankaran S, Hyer S, Shehata H.
Diabetes in pregnancy: a review of current evidence
Current Opinion in Obstetrics & Gynecology 2007 19:586-590.
43. Zachariah S, Byrne P, Hyer SL
Adult-onset Diabetes Insipidus due to trans-sphenoidal encephalocele and dysgenesis of corpus callosum
British Journal of Hospital Medicine 2008 69 4: 227
44. Patel S, Hyer S, Tweed K, Kerry S, Allan K, Rodin A, Barron J.
Risk factors for fractures and falls in older women with type 2 diabetes mellitus
Calcified Tissue International 2008 82: 87-91
45. Patel S, Mirzazadeh M, Hyer S, Barron J
PTH response to vitamin D supplementation
JCEM Online, 22 Jun 2008
http://jcem.endojournals.org:80/cgi/content/abstract/jc.2008-0350v1
46.Hyer SL, Prasad D, Newbold K, Haq M, Thway K, Wechalekar K, Harmer CL
Thyroid cancer causing obstruction of the great veins in the neck: 5 case reports and literature review
World Journal Surgical Oncology 2008 6:36-46
47. Balani J, Hyer SL, Rodin DA, Shehata H[4].
Pregnancy outcomes in women with gestational diabetes treated with metformin or insulin: a case–control study
Diab Med 2009 26 (8) 798-802.[5]
48. Hyer SL, Balani J, Johnson A, Shehata H.
Metformin treatment for gestational diabetes.
The British Journal of Diabetes & Vascular Disease 2009 9:220-225
49. Hyer SL, Newbold K, Harmer CL
Early and late toxicity of radioiodine: detection and management.
Endocrine Practice 2010 16 (6)1064-1070.
50. Patel S, Barron JL, Mirzazedeh M, Gallagher H, Hyer S, Cantor T, Fraser WD.
Changes in bone mineral parameters, vitamin D metabolites and PTH measurements with varying CKD stages
Journal of Bone and Mineral Metabolism 2011 29:71-79
51. Hyer SL, Pratt B, Newbold K, Harmer CL
Outcome of pregnancy after exposure to radioiodine in utero
Endocrine Practice 2011 17:281-6
52. Hyer SL.
Randomised controlled trial: Metformin is not significantly different from insulin for preventing fetal macrosomia in women with gestational diabetes
Evid Based Med 2011; ebmed-2011 -100121
53. Kenchaiah M, Hyer SL
Diffuse large B-cell non Hodgkin's lymphoma in a 65-year-old woman presenting with hypopituitarism and recovering after chemotherapy: a case report
Journal of Medical Case Reports 2011, 5:498.
54. Balani J, Hyer SL, Johnson A, Shehata H
Pregnancy outcomes after metformin treatment for gestational diabetes: A case-control study
Obstet Med 2012 5:78-82
55. Kenchaiah M, Hyer SL
Cushing’s syndrome due to ectopic ACTH from a bronchial carcinoid:
Case Reports in Endocrinology 2012
Article ID 215038, 4 pages doi:10.1155/2012/215038
56.Latif L, Hyer SL, Balani J, Johnson A, Shehata H.
Metformin effects on treatment satisfaction and quality of life in gestational diabetes
British Journal of Diabetes & Vascular Disease 2013 13 (4) 178-182
57.Balani J, Hyer S, Johnson A, Shehata H.
The importance of visceral fat mass in obese pregnant women and relation with pregnancy outcomes
Obstetric Medicine 2014 (7) 22-25
58. Syngelaki A, Nicolaides K, Balani J, Hyer S, Akolekar R, Kotecha R, Pastides A, Shehata H.
Metformin versus Placebo in Obese Pregnant women without Diabetes Mellitus
New England Journal of Medicine 2016 374:434-443[6]
59. Hyer SL, Wilcox H.
Charlie Gard: an ethicist in the courtroom. Rapid Response.
British Medical Journal 2017; 358; j3451 Pub 3.8.17
60. Balani J, Hyer S, Syngelaki A, Akolekar R, Nicolaides KH, Johnson A, Shehata H.
Association between insulin resistance and preeclampsia in obese non-diabetic women receiving metformin
Obstetric Medicine 2017 10 (4): 170-173.
61. Balani J, Hyer SL, Shehata H, Mohareb F.
Visceral fat mass as a novel risk factor for predicting gestational diabetes in obese pregnant women.
Obstetric Medicine 2018 p. 1–5.
Available from: https://doi.org/10.1177/1753495X17754149
62. Hyer SL, Pratt B, Gray M, Chittenden S, Du Y, Harmer CL, Flux G.
Dosimetry-based treatment for Graves’ disease
Nuclear Medicine Communications 2018 39 (6) 486-492.
63. Tran A, Hyer SL.
The challenge of thyroid hormone replacement in primary care
J Pharmacol Clin Res 2018 5 (4) JPCR.MS.ID. 555669.
64. Hyer SL, Balani J, Shehata H.
Metformin in pregnancy: Mechanisms and clinical applications.
International Journal Molecular Sciences 2018 19 (7) 1954
65. Hyer SL
Caring for women with thyroid disorders
British Journal of Midwifery 2018 26 (7) 434- 439
66. Tran A, Hyer SL, Bathgate G, Okosieme O.
Thyroid hormone replacement in primary care and the Goldilocks principle- too much, too little or just right?
Prescriber Dec 2018 30-33
67. Tran A, Hyer S, Rafi I, Okosieme O.
Thyroid hormone replacement in the preconception period and pregnancy: addressing the challenges in primary care
British Journal General Practice 2019 69 (683) 282-3.
68. Balani J, Hyer S, Rodin DA.
Novel subgroups of adult‐onset diabetes in a UK community setting
Practical Diabetes 2020 37: 32-33
69. Hyer SL, Chang J, Chuah LL, Manzoor R, Philip N
The potential for Big Data in Type 2 diabetes
Archives of Community Medicine and Public Health
Arch Community Med Public Health 2019 5(1): 039-042.
70. Nandoshvili E, Hyer SL
Thyroid disorders presenting in the Acute Medical Unit
Journal of Pharmacology & Clinical Research 2019 7 (1) 555702
71. Nandoshvili E, Hyer SL, Johri N
Partial nephrogenic diabetes insipidus associated with lithium therapy
British Medical Journal Case Reports 2019 12(9) e231093
Available at: https://casereports.bmj.com/content/12/9/e231093
72. Salota R, Lapsley M, Nabi E, Packer S, Hyer S, Dockrell M.
Time-resolved fluorescence immunoassay for urine retinol binding protein is more sensitive than polyclonal and monoclonal assays.
Annals of Clinical Biochemistry 2021 58 (5) 505-519
73. Sarre G, Hyer S, Chauhan-Whittingham P, Johnson A.
Patients’ experience of antenatal diabetic care during the current Covid-19 pandemic: an exploratory study
Practical Diabetes 2021 38 (6) 23-30.
74. Taprogge J, Gape PM, Carnegie-Peake L, Murray I, Gear JI, Leek F, Hyer SL, Flux G.
A systematic review and meta-analysis of the relationship between the radiation absorbed dose delivered to the thyroid and response in patients treated with radioiodine for Graves’ disease
Thyroid 2021 31 (12) 1829-1838.
[1] Cited in 2006 European Thyroid Association Guidelines
[2] Cited in 2002 Year Book of Endocrinology, ed, Mazzaferri EL, Mosby, US
[3] Commentary by Mazzaferri EL, Clin Endocrinol 2002, 57, 313-4
[4] Favourably reviewed by Ardilouze J-L, Mahdavian M, Baillargeon, J-P. J-P Brick by Brick: Metformin for Gestational Diabetes Mellitus? Expert Rev Endocrinol Metab. 2010;5(3):353-357
[5] Referenced in UptoDate
[6] Referenced in UptoDate
Books and chapters in books
1. Kohner EM, Porta M, Hyer SL
The pathogenesis of diabetic retinopathy and cataract.
In: Textbook of Diabetes, eds, Pickup JC, Williams G, 1991 Vol 2 Chap 57; pp564-574. Blackwell Scientific Publications, Oxford.
Medical Book of the Year: 1997
2. Hyer SL, Kohner EM.
Pathophysiology of diabetic retinopathy: Role of growth hormone and growth factors in the development of proliferative diabetic retinopathy.
In: Encyclopedie Medico-Chirurgicale 1990 10:21240 pp 1-4. Editions Techniques SA Paris.
3. Hyer SL, Kohner EM.
Diabetes in Pictures: Diabetic Retinopathy.
1990; pp1-25 Hoechst, Frankfurt.
4. Lamperelli H, Rodin DA, Hyer SL
Management of diabetes in the surgical patient
In: Association of Surgeons in Training Yearbook 1999-2000 Chapter 10: pp71-75
Royal College of Surgeons, London
5. Hyer SL, Harmer CL
Recent Advances in the Clinical Management of Thyroid Cancer
In: Trends in Thyroid Cancer Research
(Horizons in Cancer Research, Volume 37)
Ed: Carl A. Milton
Nova Science Publishers, New York, 2006
6. Hyer SL, Harmer CL
Radioiodine in Benign Thyroid Disease
In: Radiotherapy in practice: Radioisotope therapy
Ed: Peter Hoskin
Oxford University Press, 2007
7. Balani J, Hyer S, Wagner M, Shehata H
Obesity, polycystic ovaries and impaired reproductive outcome
In: Obesity- a ticking time bomb for reproductive health, Chapter 22
Ed: Tahir A Mahmood, Sabaratnam Arulkumaran
Elsevier Science, 2012
8. Hyer SL
Thyroid nodules and cancer
In: Oxford Desk Reference Endocrinology
2016
9. Hyer SL
The role of the human gut biome in obesity.
In: Practical Guide to Obesity Medicine: pp71-76
Ed: Jolanta Weaver
Elsevier Science, 2017
Abstracts
91 published abstracts from scientific meetings
Web of Knowledge [2001-2020]
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Sum of times cited: 24, 333 Average citations per item: 187
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H-index: 28 Number of publications: 130
Reviewer
Medical Advisor for: British Thyroid Foundation and NICE Committee on Thyroid Cancer: Assessment and Management
Expert Advisor for: GP Update (Ask the Experts)
Reviewer for: Current Medical Research & Opinion, Postgraduate Medical Journal, Clinical Oncology, World Journal of Surgical Oncology, Diabetic Medicine, Drug & Therapeutic Bulletin, Acta Diabetologia, Nuclear Medicine Communications